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Rifagut 400mg Tablet contains Rifaximin, a broad-spectrum antibiotic from the rifamycin class that acts almost entirely within the gut, with minimal absorption into the bloodstream. This gut-selective action makes it useful for treating infectious/traveller’s diarrhoea caused by E. coli, managing irritable bowel syndrome with diarrhoea (IBS-D), and reducing recurrence of hepatic encephalopathy (a brain-function complication of advanced liver disease) all while keeping systemic side effects low compared with conventional antibiotics.